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    Mark_Roach1985's Avatar
    Mark_Roach1985 Posts: 1, Reputation: 1
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    #1

    Nov 24, 2008, 06:10 PM
    Lortab half-life
    how long is the half life of hydrocodone, as well as how long is it detectable in in a UA?
    JudyKayTee's Avatar
    JudyKayTee Posts: 46,503, Reputation: 4600
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    #2

    Nov 24, 2008, 06:38 PM

    When you say half life, are you referring to snorting it? (That's the street slang for snorting where I live.)
    jrhea's Avatar
    jrhea Posts: 46, Reputation: 4
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    #3

    Mar 13, 2010, 07:50 AM

    Hydrocodone: Following a 10 mg oral dose of hydrocodone administered to five adult male subjects, the mean peak concentration was 23.6 ± 5.2 ng/ml. Maximum serum levels were achieved at 1.3 ± 0.3 hours and the half-life was determined to be 3.8 ± 0.3 hours. Hydrocodone exhibits a complex pattern of metabolism including O-demethylation, N-demethylation, and 6-keto reduction to the corresponding 6-a- and 6-b-hydroxy-metabolites. (See OVERDOSAGE for toxicity information.)

    When it's all said and done, approximately 3.5 to 4 hours after oral administration your body has metabolized half of the amount of hydrocodone taken.
    JudyKayTee's Avatar
    JudyKayTee Posts: 46,503, Reputation: 4600
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    #4

    Mar 13, 2010, 08:28 AM

    You have answered a post from 2008 and OP has not been back to check on thread.

    Please keep on eye on the dates.

    Also, if you are quoting from something, please state your source or else it's plagiarism.
    jrhea's Avatar
    jrhea Posts: 46, Reputation: 4
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    #5

    Mar 13, 2010, 09:38 AM

    Duly noted. Neither of my oversights will occur from this point forward. Thanks for your input.
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