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-   -   Lortab half-life (https://www.askmehelpdesk.com/showthread.php?t=284841)

  • Nov 24, 2008, 06:10 PM
    Mark_Roach1985
    Lortab half-life
    how long is the half life of hydrocodone, as well as how long is it detectable in in a UA?
  • Nov 24, 2008, 06:38 PM
    JudyKayTee

    When you say half life, are you referring to snorting it? (That's the street slang for snorting where I live.)
  • Mar 13, 2010, 07:50 AM
    jrhea

    Hydrocodone: Following a 10 mg oral dose of hydrocodone administered to five adult male subjects, the mean peak concentration was 23.6 ± 5.2 ng/ml. Maximum serum levels were achieved at 1.3 ± 0.3 hours and the half-life was determined to be 3.8 ± 0.3 hours. Hydrocodone exhibits a complex pattern of metabolism including O-demethylation, N-demethylation, and 6-keto reduction to the corresponding 6-a- and 6-b-hydroxy-metabolites. (See OVERDOSAGE for toxicity information.)

    When it's all said and done, approximately 3.5 to 4 hours after oral administration your body has metabolized half of the amount of hydrocodone taken.
  • Mar 13, 2010, 08:28 AM
    JudyKayTee

    You have answered a post from 2008 and OP has not been back to check on thread.

    Please keep on eye on the dates.

    Also, if you are quoting from something, please state your source or else it's plagiarism.
  • Mar 13, 2010, 09:38 AM
    jrhea

    Duly noted. Neither of my oversights will occur from this point forward. Thanks for your input.

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