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    berrylynn's Avatar
    berrylynn Posts: 1, Reputation: 1
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    #1

    Mar 2, 2008, 08:41 AM
    Parenting and blood types
    Is it possible for the father to be blood type O and the mother to be blood type A and have a child with blood type B? If so, how?
    Fr_Chuck's Avatar
    Fr_Chuck Posts: 81,301, Reputation: 7692
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    #2

    Mar 2, 2008, 09:03 AM
    Blood Types Tutorial

    Blood Types Tutorial
    jem02081's Avatar
    jem02081 Posts: 65, Reputation: 19
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    #3

    Mar 5, 2008, 08:19 PM
    Yes, it is possible.
    There is a rare blood type called hh (Bombay blood group) which prevent the expression of the A & B antigens. So a person who has the A and/or B alleles (genotype) will have the blood type O phenotype. See the Hh antigen system at Wikipedia (hh antigen system - Wikipedia, the free encyclopedia) for the details.

    Possible…. But how frequently does this happen?
    Well it depends. In Europeans it’s is very rare (one in a million), but more common in other places. In India (remember it’s the Bombay phenotype) it is 100X more common & on Reunion Island (Réunion - Wikipedia, the free encyclopedia) the frequency is one in a thousand.

    The genetic details for the H/h blood group are a little more completed (two homologous, linked genes (FUT1 & FUT2) with different tissue specific gene expression patterns). Check out dbRBC - Blood Group Antigen Gene Mutation Database for the details.
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