Stability of skin lightening creams
I am formulating the bleaching creams in my clinic.I use the following formula
Hydroquine 3%
Kojic 3%
Ascorby palmitate 3%
Lactic acid 2%
vitamin E 1%
Retine A 0.01%
Azelaic acid 4%
vitamin k 2%
Hydrocortison 2%
My quositon is normaly I put methyl paraben and propyl paraben as a preservave.Tetra sodium EDTA as chelator and as well as lactic acid anti bacterial.when it kept in refragarator it will not change its color but out side refragator within one week it change its color and please advice me to maintain its stability.