[davesangel]

If I took 40 mgs of hydrocodone on Friday would it be out of a urine screen by the following wed morning?

[DrBill100]

if i took 40 mgs of hydrocodone on friday would it be out of a urine screen by the following wed morning?

When it comes to drug screens half-life can be misleading. Most assays do not look for the parent drug, hydrocodone in this instance but for the breakdown products called metabolites. In this case, either morphine (screening) or hydromorphone (confirmation). In general terms, the half life of the metabolite picks up where the parent drug stops and is calculated by a more complex formula known as enzyme kinetics.

However, all traces of the hydrocodone and metabolites should be gone or below level of detection at the time described. That is assuming that you hadn't been using heavily in the days prior to the Friday dose.