I am on h-1b and got a 1099 - misc for 2006 with a nonemployee compensation of 27k. How can I file my tax forms based on it ?

You need to report the Form 1099-MISC income on Schedule C and deduct your valid business expenses on Schedule C.

The net amount left is then transferred to Schedule SE to calculate the self-employment at 15.3%.

Both schedules are submitted with Form 1040.

This is basic tax work. If you need to ask questions about this, you NEED professional tax help to file your return.