I took Tamoxifen for breast cancer 11 years ago. At that time I was taking Synthroid every day. I started to get chest pains for no reason. The nurse where I worked looked up Tamoxifen and under side effects it said, "UNEXPLAINED CHEST PAIN"! My oncologist said, of course, it could not be the Tamoxifen, but stop it if I wanted to see what happened. Guess what? The chest pains stopped. When I tried to go back on the Tamoxifen, they started up again, so I didn't take it any more. :confused: Now here's my real problem - Soon after this, my family doctor said maybe I would feel better on natural thyroid hormone rather than synthetic, so he switched me to Armour thyroid. I started to get the same kind of chest pains back again. He told me he would just put me back on the Synthroid, but I kept getting chest pains. He has tried every kind of thyroid he can think of, even the smallest amount he can give me and then I have even cut them in half and tried half in am and half at noon. I have not been able to take any thyroid since 2000 and I am almost to the point that I can hardly get out of bed. Can anyone give me any help. My doctors look at me like I am crazy!! Am I the only person in the world that this has ever happened to?? I can't play with my kids, my weight is soaring, my legs feel like lead weights! I don't know what to do!! I am getting very, very depressed!