I would like to move my toilet maybe a foot to the right and back toward wall. This is tiny bathroom and would make huge difference in moving room. Can the pipe coming straight up have an angle put on to new location?

Yes, 1 ft shouldn't be a problem. You will need to cut the piping -PVC? -, reassemble the piping and flush away!

Hold on a minute Brian, Let's find out more about this before we start with recommendations
Are you on a slab or is there space to work under the floor? What material are the pipe?
If you need more room would you be willing to replace your 12" rough toilet for a 10 " rough one? The fittings you will use to angle over will be determined by how deep the closet ell is. Back to you. Tom