My last period was the 13th off December done a urine sample last Friday afternoon at doctors came back negitaive and I have no other symptons for the menapause shpuld a do one frist thing in the morning to test if I am pregnant I am 46

Yes, please do one using first morning urine.

At 46 it could well be the "change of life" often there are no other "signs" for a few years after you stop having your period.

Urine test for pregnancy would be more accurate when it done early in the morning.but consider you are 46 it is really a miracle if you pregnant