My jeep runs on 2 cylinders, I have changed the spark plugs and wires the distributer and cap, there is no spark on the two plugs that the cylinder is out on but there is spark on the distributer. What could be the problem (there is no residue on the plugs)

Thoughts:

Lightly coat the porcelain portion of the spark plugs with dielectric grease, to prevent the plugs from shorting out. Apply dielectric grease to all connectors and ensure they are fully seated. Was the distributor OEM? Many people have problems with aftermarket distributors.

The secondary voltage is going somewhere--you don't want it to turn on the ignition system itself and ruin the distributor.