I'm 16 years old and realized I was bi in September when I started kissing my female friends, and having been in denial about finding girls attractive for some time I then realized that I was.
At sleepover the other week the 4 of us that are bi snuck out to play spin the bottle and one of my friends that was there had never kissed a girl before and the next day she told me that she had a crush on me, I thanked her for telling me but told her I didn't like her back. Since then she's been acting awkwardly and occasionally moody around me.

I like my best friend and told her so, knowing she didn't like me back. She knows how confused I am but our friendship isn't the same anymore like she promised me that it would be. She keeps making sure we only really hang out around other people and on the rare occasions we are alone it feels really awkward and we don't really talk like we used to.

I also have a slight crush on a friend of a friend who I've not met yet but she says she really likes me, but I'm not sure if she means it and we haven't talked in days when she said how much she wanted me sexually.
I said it was confusing, does anyone have any advice at all??

You have admitted that you are confused. You are very young still and things could change. Hormones to strange things. You may find years from now that you may not have been bi but very confused due to hormone changes. Take life one day at a time and good luck.

Your situation is complicated but not confusing at all. You find both boys and girls and attractive, nothing wrong wit that.

The situation with your friend is typical. You have a crush on her, if she is not bi, than it would be awkward for her to be alone with you. Take the relationship with stride. You did the right thing being honest with her (and to yourself). Do not regret it, ever.

You are in a confusing time age-wise, and throwing your new revelation into the mix is going to make it a bit more complicated, but keep you head up, you're realizing who you are as a person.

Moving forward, you may want to feel out the situation (girl or guy) and make sure the person you are crushing on will accept the idea of you being bi. Don't be too quick to catch strong feelings for someone without first knowing a relationship is possible.

Good luck.

Don't get involved sexually when you are confused about the feelings, or intentions of another. That applies to gay, bi, or straight, doesn't matter. Talking sex with any one changes any relationship, so be careful how you express yourself to others. Trust me, your friends are as confused as you are.

I will address your "friend" does not matter if bi or straight or gay, if you are a friend, and you admit there are other feelings, and they are not returned, it normally destroys that friendship, since the other person can not just shut off how they feel and now can not go back to like it was before

At 16 I question whether anyone is mature enough to begin a sexual relationship with a partner of either sex.