Im on H-1b visa from 2006-2009. Now I'm on my F-1 or student visa since 2010, Can I file for a tax return?

Yes, if you had any earned income INSIDE of the United States. You can file either as a resident as a carryover from your H-1B days, or as a non-resident alien, filing Form 1040NR.

Need to know your family status (married and/or with children) to determine which is the best way to go.