2004 F250 diesel, owned since new, never beat on, but every once in awhile I wake up to a decent amount of coolant on the ground. I have looked every where for a leak but to no-avail nothing turns up. Any help would be great!

Attach a cooling system pressure tester to the radiator, if necessary, to help locate leaks. Pressurize to 16 psi.

There may be a pin size leak (e.g. with a radiator hose) that opens up and leaks coolant, under pressure. When the system cools down, the leaking stops.