Lately a lot of guys have been like calling out to me, like either calling me cute/beautiful, asking for my number, or something like that... except I'm shy so I get nervous and I don't know what to do... mostly I just pretend I don't hear them unless they talk directly to me.
They are usually nice guys, around my age, so I feel rude or stupid just ignoring them because they are just being friendly... what would you say/do ?

Why can't you edit things on this site? Or can you?
Anyway, I'm just asking because I get really nervous when this happens as I am a very anxious person, and sometimes I avoid situations when I know this will happen because I don't know what to do or say. I don't have any friends that are guys, and I have never had a boyfriend, and I am 17, I really want to know someone opinion.

... because I'm too embarrassed to ask other people they might think I'm bragging or something.

You said you don't pay attention unless they talk to you directly.
When I was you age I never responded to boys that called out to me either. I don't think I missed anything.
Most of my friends were guys though because I didn't see then as guys but as friends. Maybe that is what you need to start doing.
Don't look at then as potential boy friends but friends, you can then be more relaxed around them and when the right one comes along you'll know it.