As for me, when I try to talk to my wife about her problem, she blows up. She then says I am the one that should be seeing a doctor. All this advice about talking to her is nice, but this is not a normal situation, remember it is a chemical imbalance, and talking it over does not work for me. In fact, I have learned to withdraw from her when she gets that way. I simply leave home for a few days. Lucky for me, I have no children to suffer through this.

It sounds like she needs to deal with the situation with her mother. Her mother was probably very sick and she was exposed to that her whole life, probably afraid that she would kill herself, and she did. Every fear she had came true. She cannot trust that she is not the same person. She is dealing daily with anxiety about who she is and whether she is a proper mother and wife, not to mention the fear of losing you both. You have to do everything you can to understand what is happening in her head. Your daughter and wife deserve that, if you really love them and want the best. Doctors are abusing these cases by over prescribing pharama and not actually helping the individual. Go to a Dr. who will take time to work through you personal experience. This is what you have to do if you really love. You have to realize that no marriage is perfect and it takes time, love and patience. We are all human with different human experiences that affect us all differently. If you stick through through this and truly try your daughter will be stronger from it. If you just leave her, your daughter will one day be trying to deal with her own issuses and realize, or think, that no love is strong enough to stay with someone who is unwell. Why bother, I have my life to live... maybe not true, but think of her perspective... am I crying too much, standing up for myself too much. She could find herself holding back and not being open with her partner due to fear of being left. It's an on going cycle that we as a society must resolve in a loving way, not a selfish way. Your wife is probably this way because her mother was never helped. Only now has society considered doing more than putting these women away, or filling them up with medication. You must play a part in saving these people not just your marriage. You can be the hero or the coward. Who are you and what are you willing to do for your FAMILY? It will be long and hard process, but you will save your daughter's life and hopefully yours and your wife's. This is serious and needs complete attention. If she sees you care so much she will begin to trust you, which could be for the first time. You may have to sacrifice a few days with your buddies, but isn't it worth it? You decide how you want to look back at this. If she had cancer and was strange due to the medicine, would you leave her? It's no different, she is sick and needs help.