Recently I was UA tested for Oxycodone.

The test came back negative, the test papers said - U Oxycodone Lvl: Oxycodone detection limit 100ng/ml.
Reference Range: Negative

I am taking 10mg Oxycodone every 12 hours. The test was taken almost exactly 12 hours from my last dose. I cannot tell you what kind of trouble this has caused, that is not until I have seeing how many other people have had this problem.

What I am not finding is - what level of ng/ml should someone taking 20mg Oxycodone per day show on a UA test??

Please help!

I think it wouuld come back below the detection limit that you said.

I'm basing it on:
1: Elimination of 20% (alo in the below document)
2. Page http://www.purduepharma.com/PI/Presc...xycontin.pdf6; here:

You won't even gain much if it were taken after an hour of dosing. My calcs seem to indicate at or slightly below the detection limit.

It should be gone in 20 hrs or so. 5x the half-life.

And what type of problems is this causing ?

Quote:

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Originally Posted by Fr_Chuck

And what type of problems is this causing ?

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Is this how I answer you??

Yep, you figured it out. "Answer this question" means "Reply to this thread"

This is new.

Not sure if your question is serious?

The problem is, that it appears that my doctor doesn't know how to do what I now know is called, a "drug compliance test", as opposed to a "drug abuse test".

The problem is, that now I am going to be labeled as either a drug abuser or a drug diverter(?) In other words someone that is either selling or giving the drugs that they are prescribed, to someone else. I do not know about you Father, but, this is a problem to me.

Please, I do not mean to sound harsh. It appears to me that I will now be labeled because my doctor is ignorant. However, I do not want to do the same thing to him that he has done to me. In other words, what I am attempting to do is find out what should the test have been, so that I have proof when I talk to him. Maybe it will spare someone else from going through what he has put me through. If he had just taken a little time check out the possible errors, I believe that he would have found that many of these tests do not show accurate for compliant users.

Thank you

I would suggest requesting another test. If the doctor ran the wrong test, and you can prove it, then it's not your fault the test didn't show the drug in your system.

Thank you for your reply, I appreciate your input. But, I still do not understand how to do the math? Is there some other way that I can figure it out?

lab techs have to factor in several variables when they do any test. You age, weight, dosage, when you last took a dose, the drug they're testing for, how long the drug stays in your system, how the drug is administered, how long it takes to disperse throughout your system, and who knows what else. Only someone with experience in the field would be able to explain how the reach the final result.

if the test was more along the lines of the 'pee in a cup and they drop a test strip in' variety, then it's less exact anyway.

I would suggest talking to your doctor about it. Explain that you've done further research and you believe he administered the wrong test. Agreeing to a random test, with only an hour or two of notice, may get the doctor to agree more readily to a retest.

just curious; was the test administered because of probation, or some other legal action, or just your doctor's way of making sure you're taking your meds?

I did "did the math" quicky by;

1. Finding the plasma concentration at 12 hr for 20 mg Oxycodone. Your taking them wierdly, so I figure it has to be at least that much (I'm overestimating). Note the units. It's a log plot, so reading/guessing values from the graph is tough.

2. You have to do some deciliter and ml conversions to get the units right. Online Conversions, Unit Conversions

3. Then from the same reference there is mention of renal clearance. That I believe was about 20%, so you multiply the result above by 20% or 0.2.

Urine is detectable longer, but I still feel that the amount your taking may be under the detectable limit.

Quote:

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Originally Posted by hheath541

i would suggest requesting another test. if the doctor ran the wrong test, and you can prove it, then it's not your fault the test didn't show the drug in your system.

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Thanks, I do appreciate your response.

I wish it were that easy. He said he stood by his test, that it was accurate, and he is of the opinion that I am not taking what he prescribed and he is no longer going to help me manage my pain.

It is through the research that a friend (who just happens to be an RN) brought to my attention, that doctors do not necessarily know how to do compliance drug testing. In other words drug testing for people who are on pain management programs. Also, that there are a great many people who are going through the same thing that is happening to me.

That is why I am looking for a formula to tell what level a person who is taking a maintenance level of a prescription should test at. I do not want to falsely accuse my doctor (who is a GP, and not a pain management specialist).

I just want to know what happened?

Thanks again, I appreciate it!

Quote:

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Originally Posted by hheath541

lab techs have to factor in several variables when they do any test. you age, weight, dosage, when you last took a dose, the drug they're testing for, how long the drug stays in your system, how the drug is administered, how long it takes to disperse throughout your system, and who knows what else. only someone with experience in the field would be able to explain how the reach the final result.

if the test was more along the lines of the 'pee in a cup and they drop a test strip in' variety, then it's less exact anyway.

i would suggest talking to your doctor about it. explain that you've done further research and you believe he administered the wrong test. agreeing to a random test, with only an hour or two of notice, may get the doctor to agree more readily to a retest.

just curious; was the test administered because of probation, or some other legal action, or just your doctor's way of making sure you're taking your meds?

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That's OK!

The test was to see if I am taking a prescribed medication. And, yes it was a "pee in a cup" test.

Also, you are correct, this is a question for someone who is probably a lab tech. I no longer feel comfortable with my doctor, after the few questions that I could manage to ask while I felt like my integrity was being flushed down the toilet. Have been having a hard time finding an alternate source to get the information needed.

Thank you for the random test idea! That is great! I wonder what response I will get??

By the way, as long as you brought up the "why" of the test, I some how feel compelled to further add that I am a middle aged frumply (at least since I have ben laid up for two years) female, who in no way fits any resemblance to a druggy. I only want to get enough pain relief to be able to get back to what at least resembles my former very active life.

Thanks again for your thoughts.

Hope that all this isn't too much information. I really didn't expect to see of the responses that I have received - I am very thankful.

OK, here is a better explanation.

The PDF that I referenced is a bad link. Detete the characters after the PDF.

1 dl = 100 ml, so you need to multiply the values of the graph on page 6 by 100 to change scales to ng/dl, but it's still urine.

Later in the document it says the renal clearance is up to 19%. I used 20%. Therefore the 1 on the graph is 1*100*0.2 or 20 and the 10 on the graph is 10*100*0.2 or 200 ng/dl in urine.

If your heavy, I would assume that 20% is a high number.

The graph is a log scale.

Oxycodone is a semi-synthetic opiate and none of the semi-synthetics are detectable on standard UA panels, except in very high dosage. Your dosage is low.

Oxy, and other semi and synthetics require a special panel test. Your test results were probably an error on the part of the testing agency by providing the wrong panel (for opiates) and shipping the mistake to a laboratory absent appropriate instruction.

You may view the proper procedure(s), Urine Drug Testing, Quick Reference, on line, at http://www.familydocs.org/assets/Pro...T_Ref_Card.pdf This error in relation to Oxy and many other of the S/S class are far too frequent and unnecessary.