I need to install a new shower base over a concrete surface, however the surface is not a normal size for a standard shower base nor is the drain located in the center of the floor. How do I re-route the plumbing to reach the drain, do I elevate the shower base using 2 x 4's and cement boards to run the plumbing?

The most practical way would be to break out the concrete and make a trench through the concrete to install the drain in the correct place.