I have a Mega 105WR router and 2 x ISPs (Telkom & Afrihost).

No problems switching between the two, until 01 January 2010. Now I can only access the Telkom ISP no matter how many times I try to change the setup for Afrihost. Rebooting the router also does not help.

Is there an easier way to do this without using the router setup? I would think that there is software available to address this?

You could forget the router and install a second Ethernet adapter. This way you could access both right from your computer. You could just disable one and use the other, or vice a versa.