Can I use a pioneer vintage receiver sx 1280 with cerwin vega vs 100 speakers?

Be sure the Impedance Matches.
8 Ohm Output to 8 ohm speakers.

If you have 4 8 ohm speakers and Amp has 4 ohm impedance, you can wire 2 8 ohm speakers in parallel to get 4 ohms.

If you have 4 4 ohm speakers and amp handles 8 ohms, you can wire 2 speakers in series for each channel, plus of 1 speaker to minus of other speaker.