I have XP on 160HD - IE7 etc.

This just started today after months and years problem free. Cannot head towards (My Computer).. it freezes. Will not display my Pindrive or contents. Does not open as before when I stuck it in the USB. What could possibly be the problem?

Have you restarted the computer since started?

Any changes that either happened or that you perhaps made to your computer around the time that the problem started; particularly any Software or Hardware that you installed or setup.