My father have four brother and four sister,is it possible that my grand father is creat a paper there he was mention his home he given his two son

Yes. A person can will his property to whomever he chooses.

Where are you located? If in the U.S. yes your grandfather can will the property to whom ever he wants (provided there aren't any outstanding bills that need to be paid using the house to get money for the estate). However, if outside of the U.S. we need to know what country because different countries have different laws.