What the total percentage of penalties and taxes that needs to be paid to withdraw the money froom a 401 k plan

We can't answer that since it depends on your total income for the year. It also depends on whether your state will tax the income.

We can tell you that there will be a 10% penalty and that the plan will withhold 20% towards federal taxes.

Beyond that it depends on your specific situation. The total bite could be 40-50%.