How can I stop McAfee or my computer protection from not allowing me to open up Spotify.

McAfee has posted this response:

"McAfee has been made aware that some users are experiencing an issue with Spotify. A fix will be provided in today's regular signature file update. McAfee would like to apologise to any customers affected by this issue and reassure them that this is being addressed as a matter of urgency."

I think you'll be able to download an update within the next couple of days and everything will be forgiven (or not).