Works 7.0. I have two hard drives with my files on the E: drive. Works always looks to C:/MyDocuments. I want to change it to look at E:/MyDocuments. Easy to do in Office. How can it be done in Works ?

In your operating system, right-click on "My Documents" and select "Properties". Under the "Target" tab, you can change what the computer knows is "My Documents". You cannot change "My Documents" on a program level, only on the operating system level. Some programs allow you to change the default directory.

Just to point out here, Perito's advice is the best way to deal with this. But some programs (Office as you note) do permit setting the default directory for documents.

Microsoft has an old post (1994) about how to change the default folder for Microsoft Works, but there's some incorrect information in it.

Works: How to Change the Default Folder in Which Files Are Saved

Basically what you do is find a shortcut that you use to start Microsoft works. That shortcut can be in the Start Menu or on the Quick Launch bar or on the desktop or anywhere else. Right-click on the shortcut and select "Properties". In the area that says "Start in:", enter the full path to the directory where you want the files to be saved. Each time you launch Microsoft Works from that shortcut, the default path for files will be in the directory you specified.