I am currently on depo. My next shot is due tomorrow which I have an Appt to get it however.. I had unprotected sex yesterday and I wasn't sure if I should take the morning after pill just to be sure and If I take the pill and then get my shot will it affect my hormones too much? Should I just wait and get my shot?

You should get your shot on schedule. If you are having the shots at the regular intervals, there should be no reason to worry about additional birth control, even with unprotected sex since that is the point of having the injections. You can always explain the situation to your doctor before you are given the shot.