Hard drive C or second drive does not open by double clicking

While right click on the drive it shows auto play then It must be infected by virus and scan your computer with good anti virus like avg anti virus.

Hey it probably may be a virus. I suggest that you delete the autorun.inf file from all your drives. To do this, enter the command prompt, select the Drive and in the command mode type the following.
ATTRIB Autorun.inf -H -S -R.
If the file is found in the Drive then give.
DEL Autorun.inf.

If double clicking on the C:\ doesn't open it, you can use the work around by either right clicking on the Start button and clicking on Explore all Users, or by pressing Windows Key + E at the say time. Either action will open up Windows Explorer and allow you to browse your computer's C:\.

If you suspect that it is due to a virus or spyware, update your current AV software and download Malwarebytes and Spybot S&D 1.6.2 and update, reboot and press the F8 key repeatedly to get the alternate boot screen, select boot into safe mode with networking. Log on to the current windows installation and perform full system scans and remove any issues found.