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Getting rid of calluses, interestingly enough, can actually worsen your health overall, rather than improve it. Why? Because calluses are your body's natural defense against friction and pressure that is being constantly applied to any particular area of your skin.
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A weekly soak and scrub will help to treat and get rid of calluses that have already developed.
For those calluses that are already present, the most common and medically sound treatment is a weekly soak and scrub. This usually involves soaking your feet or hands in a warm vinegar (try 1 cup of apple cider vinegar) and water solution for 10 minutes and then using a pumice stone to scrape away dead skin. If you have particularly sensitive skin or you're diabetic, or you suffer from a circulation problem in your extremities, you should avoid using vinegar and use plain, lukewarm tap water instead. Be patient and don't remove too much calluses at one time.
I wish for you only the best!