1 out of 6 8 week old labs won't eat or play today... been sleeping for 6 hours... he did pee once and just drank some water. Was going to give all shots tomorrow... should I give him his ?if not ,should he go to the vet... what could be wrong?

Forget the shots, take him to the vet asap. Is he the runt of the litter, maybe? It is good he is drinking, if he was really sick he wouldn't be doing anything.