So I've been browsing around several skin lightening forums for a few weeks now and found from 2 people who claimed that the formula for permanent depigmentation for people with NO vitiligo is

Monobenzone 20% + Benzylarbutin 20% + Tretinoin 0.1%

Anyone have any experience with this? I thought monobenzone made repig spots come back after a few months?

People who claim this

1. https://www.askmehelpdesk.com/skin-l...-211660-2.html

2.
Is anyone bleaching with benoquin? - Yahoo!7 Answers

RUBBISH !

Pure Mono depigs surely

Benzyl? Bull

Tretinoin is very effective !

Monobenzone does harm or possibly destroy some/many melanocytes, but the chances for re-pigmentation are slim in an overall area. (30% if you prevent direct UV exposure for lengthened times, thus good sunscreen and a melanin maintainer are necessary.)

Benzyl-Arbutin is a non-existant chemical which has no scientific effect on the skin. (It's not related to, nor reduces the size of your melanocytes.)

Tretinoin is the acidic form of vitamin A. It's main target is reducing acne, and it's main use isn't for a skin lightener. (Some claim it works, others don't.)

Quote:

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Originally Posted by moganrasa

Monobenzone and Tetrinoin works synergistically. Arbutin makes brown patches if used on skin after bleaching with monobenzone. I f you have started with monobenzone, avoid Arbutin.:cool:

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Alpha Arbutin does not cause "brown patches", it prevents them through it's inhibitory properties (Tyrosinase). It may give the illusion of "brown patches" under low light, but in the long run it provides that your melanocytes do not fight back, and if they do, it doesn't ruin the effects of depigmentation provided by Monobenzone or other lighteners. (Preventing proper melanogensis that may lead to melanin production or melasma.)