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-   -   What is transdifferentiation (https://www.askmehelpdesk.com/showthread.php?t=189149)

  • Feb 28, 2008, 02:58 AM
    veena123
    What is transdifferentiation
    Do somebody know about transdifferentiation... wht does that mean..
  • Feb 28, 2008, 04:04 AM
    nicki143
    Wikipedia has a page on this do not understand it myself but may help you
  • Feb 28, 2008, 09:11 PM
    jem02081
    The conventional model of differentiation is when a cell (stem cell) can develop into anther another cell typically be means of series of intermediate cell types. Each intermediate cell type has fewer choices in what it can become until; ultimately, the cell is committed to becoming 1 final / terminal / differentiated cell type. Think of a tree. The stem cell would be the trunk (stem) & the end of each branch would be a differentiated cell type.

    Transdifferentiation is when a cell jumps from one branch to another. In the conventional model this doesn’t happen. Differentiation occurs when a cell can no longer form both cell types.
    So does it happen naturally? I don’t know
    Could a cell be bioengineered to transdifferentiate? Possibly
    Ultimately, could a cell be engineered to produce all cell types?
  • Feb 28, 2008, 09:37 PM
    oneguyinohio
    I could be wrong, but I was thinking that researchers are trying to do this with stem cell research involving embryos... I could be way off on my thoughts... so if anyone knows please share as I love learning more about it...

    What I had read is that they were working toward getting stem cells to be able to reproduce and repair damaged cells and tissues in the body... Is this the same process as transdifferentiation?

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