We were asked:

If 527 - 142 = 345
And 901 + 522 = 223
Then 148 - 253 = ?

Can anyone help me on this?

Do you have any more information? Is that all your were given? Because the first 2 sums are clearly false.

Yes that's all we were given

Is it meant to be algebra i.e. the numbers should be letters?

What are you studying at the moment?

It seems that the numbers are meant to be interpreted as 12 hour clock times:

5:27 - 1:42 = 3:45
9:01 + 5:22 = 2:23(pm)

Knowing that you should be able to work out the aswer to the third sum.

Thanks

Is it 1055?

Yup :)