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-   -   Raised liver enzymes (https://www.askmehelpdesk.com/showthread.php?t=168670)

  • Jan 4, 2008, 07:52 AM
    scodaman
    Raised liver enzymes
    My last bloods showed a ggt of 170 and an alp of 240,is this bile duct damage from whipples surgery 10 years ago.If so will it get worse and cause liver damage.
  • Jan 4, 2008, 10:35 AM
    J_9
    An increase in GGT (Glutamyltransferase) can be caused by:
    *Cirrhosis
    *Diabetes with hypertension (high blood pressure)
    *Hepatitis
    *Hepatobiliary tract disorders
    *Hepatocellular carcinoma
    *Hyperthyroidisim
    *Obstructive liver disease
    *Pancreatitis
    *Kidney transplant
    or
    *Significant alcohol ingestion

    An increase in ALP (Alkaline Phosphatase) can occur in:
    *Aplastic leukemia
    *Chronic inflammation
    *Down syndrome
    *Hairy cell lukemia
    *Hodgkin's Disease
    *Lukemia (acute and chronic lymphoblastic)
    *Myelofibrosis with myeloid metaplasia
    *Multiple myelomia
    *Polycythemia vera
    *Pregnancy
    *Stress
    OR
    *Thrombocytopenia

    I don't see a corrolation between the two tests, I would need more info than these two tests to go on. However, there are medications that can cause abnormal increase in these two lab values, such as acetominophen and steroids just to name 2.

    Are you on any medications? Were other lab tests performed that you have the results of? A WBC (white blood count) would be helpful, as would a BUN and Creatinine.
  • Jan 4, 2008, 01:43 PM
    scodaman
    As my doctor+also my consultant have never even asked me if I drink alcohol I assume it is not significant-doctor said this is not drug related but is due to surgery.when these 2 enzymes are raised I think it is due to cholystasis-does anyone know if this is correct?alt is sometimes marginaly raised.

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