Epileptic dog with diabetes insipidus
I have a staffie who is 4.5years old he has been epileptic since jan 07 he has fits every 28 days and they are multiple the most being 12 in one day.he always cluster fits. He is being medicated with phenabarbatone(240mg/day) and potassium bromide(650mg/day) however he still has the seizures.when he has the fits I have to give him diazipam to try to stop any further fits occurring however I am not convinced this makes any difference and last month he had 40mgs although for his weight the dose should only be 4.8mgs and the seizures seem to only stop when he's good and ready!he's had blood tests and nothing has been found although for some reason the theraputic level of the phenabarbatone in his system was very low at 17(the range is between 15 and 45) even though he is taking such a huge dose of medication.I mentioned to my vet that all the dog does is drink and pee constantly and had mixed reasons given for this such as damage to the brain from the seizures making the dog psyco and that the medication may make him thirsty.the dog has been getting larger and swells through the day as his water consumption grows and on somebody else's advice(not a vet) I had him tested for diabetes insipidus which he has now been shown to have although no treatment has started yet I would like to know if there could be any link between the epilepsy and the diabetes insipidus as my vet is saying no but I think his medication is getting diluted as he pees about 30 times every night and he always has his fits in the middle of the night whilst asleep with nothing to stimulate him it doesn't make any sense to me