I have a huge problem that upsets me to the point of depression. No matter what I do... and no matter how many pounds I've lost...

I have always had huge hips, thighs, a huge butt and worst of all - cellulite on d outer thighs/hips.

Help!

You could be eating too much bad fat vs good fat causing fat burning leptins to decrease.
Nutrition - Good Fat vs. Bad Fat

You could need a higher metabolism
Speed Up Your Metabolism

It could be your thyroid
The Fat Flush Plan - Google Book Search

There are many things it could be.