I have an asus motherboard P4V800-X , when I go to hibernate , the mouse still works and when I move it or press any key on the keyboard the computer works
I want to disable this option because some time I move the mouse accidentally , and I don't won't the computer to work

Are you sure you are talking about hiberation or just sleep mode. Generally they are not the same. Sleep mode is the first stage. In sleep mode the mouse remains active and mouse movements will awake the computer. Hibernation is deeper and may need to be specifically entered or entered only after a longer period of inactivty. In hibernation the mouse is generally disabled and it requires pressing the power button or Ctrl+Alt+Del to awake.

Systems vary on this and you may what to consult your manual or manufacturer for help.