A slight itching come in my foreskin and it started inflamated and having slight pain
It reduces the size of the hole too.
Around 2 years back I got this problem but after 4-5 weeks it has gone. Now it is come again two weeks back it is gone and again started. Now I cannot pull back the skin at all. A very small ole only. But passing urine I am not facing problem. What is the solution for this? What medicine I can use?

If you are uncircumsized you have a higher risk for bacteria to thrive in the genital area. My guess would be that you may have some kind of infection. My best advice would be to talk to your doctor.

Maybe you need to see the doctor about this. Most otc itching medications, will warn you not to put inside of genitals. I am assuming that you are not circumised. Also eat plenty of yogurt. This is good for keeping your system balanced. Hopefully you practice safe sex, if you sre sexually involved.