Also "windows cannot find 'helpctr.exe'
What is going on?

What are you trying to do ?
The more information you give the better we can assist with your issue.

I was trying to: start - run - msconfig

From you title you mentioned msconif.exe which is spelt incorrectly.
To be honest an easier way to adjust your startup programs is a great FREE program called CCleaner, available here: CCleaner - Home

This also cleans "junk" files from your system and cleans your registry.