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  • Mar 25, 2022, 03:19 PM
    jlisenbe
    Well, you have not supported your testosterone bath idea, nor have you given any hormonal reason why a given woman feels she is a male.

    Best wishes.
  • Mar 25, 2022, 03:42 PM
    Wondergirl
    How do transgender folk harm you? Why are you so against them? You couldn't pick them out of a crowd anyway. Live and let live.
  • Mar 25, 2022, 06:15 PM
    Wondergirl
    Quote:

    Originally Posted by jlisenbe View Post
    Well, you have not supported your testosterone bath idea

    The Y Chromosome & Testicle Development

    Testicles and ovaries develop from the same gonad tissue in a developing baby. At around the seventh week of pregnancy the SRY gene (which is only found on the Y chromosome) signals the gonad tissue to become a testicle. Since only the Y chromosome has the SRY gene, it is the Y chromosome that dictates a baby will be a boy.
    Once the SRY gene triggers the gonad to become a testicle, the testicle begins to produce three main hormones:

    • Testosterone
    • DHT (dihydroxytestosterone)
    • MIH (short for Mullerian Inhibiting Hormone)


    These hormones cause the creation and development of the male reproductive system and the female reproductive tracts to regress.
    https://www.menshealthhandbook.org/fetal-development

    What happens to a female human fetus exposed to excess testosterone?
    Scientists have long known that prenatal exposure to androgens, such as the hormone testosterone, causes genital defects in females. Androgens act as masculinizing hormones, directing formation of male genitalia and preventing formation of a vaginal opening in boys.
    https://findanyanswer.com/how-is-a-f...o-testosterone
  • Mar 26, 2022, 05:03 AM
    tomder55
    This is too deep for me .I am willing to venture that the vast majority (or at least a plurality ) of Dem voters knows what a woman is .
  • Mar 26, 2022, 06:06 AM
    jlisenbe
    WG did try, but she provided nothing to support her contentions about a "testosterone bath" or TG people having a different natural hormonal makeup than others. This, for instance, is just basic ninth grade bio. "Testicles and ovaries develop from the same gonad tissue in a developing baby. At around the seventh week of pregnancy the SRY gene (which is only found on the Y chromosome) signals the gonad tissue to become a testicle. Since only the Y chromosome has the SRY gene, it is the Y chromosome that dictates a baby will be a boy." Yes, and water is composed of hydrogen and oxygen. There is nothing in science to support her idea that TG individuals have a different hormonal makeup than others. Her own link, in fact, provided the concept that X and Y chromosomes determine the sex of the new human. Perhaps she should send that to the SCOTUS nominee.

    This quote would only support the idea that a woman with some sort of defect in her sex organs might have been exposed to excessive levels of testosterone in the womb. It does NOT support the idea of that being a cause of TG. "Scientists have long known that prenatal exposure to androgens, such as the hormone testosterone, causes genital defects in females. Androgens act as masculinizing hormones, directing formation of male genitalia and preventing formation of a vaginal opening in boys."

    So WG is basically providing answers to questions that have not been asked. And no, that is not spitting on her link. I'm simply pointing out that she provided nothing in the way of support for her ideas.
  • Mar 26, 2022, 09:34 AM
    Wondergirl
    It was Part One.
  • Mar 26, 2022, 09:37 AM
    jlisenbe
    It was part zero.
  • Mar 26, 2022, 09:41 AM
    Wondergirl
    Stay tuned.
  • Mar 26, 2022, 10:21 AM
    jlisenbe
    OK, but you will need to come up with something that supports your assertions. Just random facts of science won't get it done.
  • Mar 26, 2022, 10:36 AM
    Wondergirl
    Those random facts are the basis. There will be a test next Tuesday.
  • Mar 26, 2022, 03:55 PM
    Wondergirl
    "The default gender in the womb is female, which is perhaps hardly surprising given that the womb is an environment awash with female hormones. A genetically male fetus will therefore de­velop the female form of sexual organs until ‘maleness’ is switched on by the SRY* gene on the Y chromosome, and the fetal testis starts to develop and then produce testosterone." ["testosterone bath"]

    In the same article:
    "A clue about the effect of hormones in the womb comes from the Diethylstilboestrol (DES) tragedy. DES is a synthetic oestrogen. From the end of the Second World War on, it was prescribed to pregnant women mainly in the US, in the mistaken belief that it would prevent miscarriage...DES was a potent carcinogen and twenty years on was dis­covered to cause a rare and sometimes fatal type of vaginal cancer in some young women who had been exposed to it in the womb, as well as infertility in others. It was withdrawn from use in 1971. The cancers affected females but there was also a curious effect on males exposed to DES: they were more likely to show female-typical behaviour such as enacting social themes in their play or caring for dolls." [transgender]
    https://healthdoctrine.com/hormones-...e-development/

    *The sex-determining region Y (SRY) gene is located on the Y chromosome. SRY is the main genetic switch for the sexual development of the human male. If the SRY gene is present in a developing embryo, typically it will become male.
  • Mar 26, 2022, 07:29 PM
    jlisenbe
    Quote:

    an environment awash with female hormones.
    I thought it was a "testosterone bath" which is a MALE hormone. Are you confused now? Which one is it?

    DES was withdrawn in 71 so anyone under fifty has no side effects from that, but even at that your article was primarily about CANCER, not TG.

    Your final paragraph is just more gobbley gook about general principles in bio and has nothing to do with TG or "testosterone baths".

    I'm done with this foolishness. You have zero. You are just frantically throwing mud up against a wall in the hope that something will stick. It did not.

    And to say again, I say that with no malice at all. I'm convinced you know all of this already. You simply have no support for your ideas.
  • Mar 26, 2022, 08:03 PM
    Wondergirl
    Quote:

    Originally Posted by jlisenbe View Post
    I thought it was a "testosterone bath" which is a MALE hormone. Are you confused now? Which one is it?

    Ah, the cherry-picker, literalist at work again!

    We start out as female. Estrogen. By six weeks or so into the pregnancy, the fun begins with testosterone!
    Quote:

    DES was withdrawn in 71 so anyone under fifty has no side effects from that, but even at that your article was primarily about CANCER, not TG.
    The cancer affected the offspring of the DES recipients, including TGs'. Read the entire article, please.
    Quote:

    Your final paragraph is just more gobbley gook about general principles in bio and has nothing to do with TG or "testosterone baths".
    Read the entire article.
    Quote:

    I'm done with this foolishness. You have zero. You are just frantically throwing it up against a wall in the hope that something will stick. It did not.
    Read the entire article.
  • Mar 27, 2022, 05:18 AM
    jlisenbe
    If you have anything to offer other than asking me to read what I guess you could not figure out how to post, then go for it. Yet again I'm sorry, but what you posted offered nothing of substance at all. You have theories without support.

    Quote:

    By six weeks or so into the pregnancy, the fun begins with testosterone!
    This is really bad. Your own post shows that is not true. "...given that the womb is an environment awash with female hormones. A genetically male fetus will therefore de­velop the female form of sexual organs until ‘maleness’ is switched on by the SRY* gene on the Y chromosome, and the fetal testis starts to develop and then produce testosterone."

    Must I tell you again that testosterone is NOT a "female hormone"? There is nothing there about a "testosterone bath" in the womb. It is the MALES and males only which it refers to having testosterone. Is your knowledge of science that deficient??

    The plain truth is very apparent. You are so invested in your TG beliefs that you are desperately pulling at straws in the hope of accidentally finding something helpful to your beliefs. It is a sad venture to have to watch, and one which has been wildly unfruitful for you.

    If you ever post anything of substance on this topic, then I'll respond. Otherwise, stick to grammar. You're good with that. Science? Fraid not. Your understanding is too, too limited and your bias overrides your common sense, a fatal flaw in science. It's like telling someone, "You should put a period there, man, because, like, I really love periods!!" (<:
  • Mar 27, 2022, 09:09 AM
    Wondergirl
    I see you read and understand other things the same way you read and understand the Bible.

    Maybe you will attend classes in heaven and learn how to read more carefully.
  • Mar 27, 2022, 04:14 PM
    tomder55
    https://scontent-atl3-2.xx.fbcdn.net...Tw&oe=6246C75C
  • Mar 27, 2022, 04:20 PM
    tomder55
    https://scontent-atl3-2.xx.fbcdn.net...XQ&oe=6246D406
  • Mar 27, 2022, 07:42 PM
    jlisenbe
    Those are hilariously accurate. Perhaps she was using the literary device of depending on the compliant press for support?
  • Mar 28, 2022, 03:29 AM
    tomder55
    To sum it up ;Jackson knows what a woman is . She lied about it because her confirmation is a sure thing but she does not want to anger the Dem pc/woke constituency . If she is so transparently lying about something like this then what else is she lying about ? I have surmised that her biggest lie in testimony is that she has no judicial philosophy and that her methodology is that of a textual originalism who knows the limits of the power of the judiciary . The decisions she has made that I have read do not support that of a judge who believes in judicial restraint . They support the conclusion that she is an activist judge who injects her political beliefs above determining if a law or the application of the law is constitutional .
  • Mar 28, 2022, 05:20 AM
    tomder55
    btw ;how did Carol King know how it feels to be a 'natural woman' ? She is not a biologist.
  • Mar 28, 2022, 05:24 AM
    jlisenbe
    How did Helen Reddy know what it means to say, "I am woman, hear me roar?" She was likewise not a biologist.

    It is sometimes disheartening to see what kind of utter nonsense we Americans will accept.
  • Apr 2, 2022, 05:18 AM
    Curlyben
    It's not just elite sports in the USA, but in UK as well..
    https://www.bbc.co.uk/sport/cycling/60960213
  • Apr 2, 2022, 10:18 AM
    Wondergirl
    That's why hormones have been and are continuously taken, to change gender characteristics.
  • Apr 2, 2022, 11:16 AM
    jlisenbe
    By the time you are twenty, it's too late for that to be completely effective. The science is clear on that.

    "The recent International Olympic Committee (IOC) (2015) guidelines allow transwomen to compete in the women’s division if (amongst other things) their testosterone is held below 10 nmol/L. This is significantly higher than that of cis-women."

    "We conclude that the advantage to transwomen afforded by the IOC guidelines is an intolerable unfairness."

    https://jme.bmj.com/content/45/6/395

    The paper stated healthy male test subjects “did not lose significant muscle mass (or power)” when their testosterone levels were suppressed below the International Olympic Committee guidelines for transgender athletes of 10nmol/L.

    https://thefederalist.com/2019/08/08...ne-injections/
  • Apr 2, 2022, 11:27 AM
    Wondergirl
    No, the science isn't clear on the that!!!

    The Federalist??? Surely you jest!
  • Apr 2, 2022, 12:24 PM
    jlisenbe
    The Federalist? Yeah. All they were doing was referring to an article from the Journal of Medical Ethics. And they had actually READ the research!!

    You can say the science isn't clear all you want, but other than just asking us to take your word for it, you would need to appeal to research. You have not demonstrated an ability to do that. Not trying to be ugly, but we both know that is true.
  • Apr 2, 2022, 12:51 PM
    Wondergirl
    I have, but you spit on it because it came from a "liberal dem" (me, hahahaha) and you cherry-picked.
  • Apr 2, 2022, 12:55 PM
    jlisenbe
    You are referring to the article you posted that actually contradicted your fake idea about a "testosterone bath". So I will wait patiently. I've grown accustomed to it.
  • Apr 2, 2022, 01:25 PM
    Wondergirl
    It didn't contradict, but then we know you didn't read it honestly and with an open mind, you ol' literalist, you.

    "The default gender in the womb is female,
    which is perhaps hardly surprising given that the womb is an environment awash with female hormones. A genetically male fetus will therefore de­velop the female form of sexual organs until ‘maleness’ is switched on by the SRY gene on the Y chromosome, and the fetal testis starts to develop and then produce testosterone."
  • Apr 2, 2022, 01:36 PM
    jlisenbe
    Quote:

    "The default gender in the womb is female, which is perhaps hardly surprising given that the womb is an environment awash with female hormones.
    Not only does this not support the idea of a "testosterone bath", it proposes the exact opposite. You know so little science.

    Quote:

    ‘maleness’ is switched on by the SRY gene on the Y chromosome, and the fetal testis starts to develop and then produce testosterone."
    And this gives us the startling news (to you) that males produce testosterone, even in the womb. It in no way supports your fake idea that all unborn children are subject to a testosterone bath.

    I'm done with this. Any even semi-educated person reading this will immediately see that you have nothing and actually contradicted your own idea. That you cannot see that speaks both of your lack of knowledge in the arena of science and an unwillingness to acknowledge information that doesn't support your preconceived notions.

    And besides all of that, I get tired of trying to explain these things to you repeatedly. It gets old, and I end up resorting to sarcasm which tends to be unkind, so it just doesn't pay.

    Stick with grammar. It's your strong point. I will agree any day that you are very good with it.
  • Apr 2, 2022, 01:57 PM
    Wondergirl
    Quote:

    Originally Posted by jlisenbe View Post
    Not only does this not support the idea of a "testosterone bath", it proposes the exact opposite. You know so little science.

    Every embryo starts out as FEMALE!!!!

    Quote:

    Originally Posted by jlisenbe View Post
    And this gives us the startling news (to you) that males produce testosterone, even in the womb. It in no way supports your fake idea that all unborn children are subject to a testosterone bath.

    That's how some of those female embryos develop male sex organs. Testosterone, weeks 7-9.
  • Apr 2, 2022, 02:03 PM
    jlisenbe
    That is not what your article is saying, but even if it was, it would in no way support your contentions.

    This is research from Johns Hopkins U.

    Quote:

    "Every developing embryo, irrespective of its sex, at one point contains both male and female reproductive tracts, referred to as the wolffian duct and the müllerian duct, respectively. If the fetus produces testosterone and the anti-müllerian hormone (AMH) gene products from the Y chromosome — these molecules elicit cellular signaling events that lead to the destruction of the female müllerian ducts. The wolffian ducts subsequently develop into male reproductive organs, such as the seminal vesicles, vas deferens and accessory structures. In the absence of testosterone or AMH, the wolffian ducts degenerate and the müllerian ducts develop into female reproductive organs including the fallopian tubes, uterus, cervix and upper vagina. These pathways were first identified and elucidated in the 1940s by the French endocrinologist Alfred Jost, who conducted intricate experiments using rabbits and showed that female development is a "default" pathway that needs to be actively overridden for the development of male sex organs.
    https://biomedicalodyssey.blogs.hopk...ns-out-a-girl/

    Quote:

    That's how some of those female embryos develop male sex organs. Testosterone, weeks 7-9.
    Please read your own articles. I've already posted the quote above. You are being ridiculous. "and the fetal testis starts to develop and then produce testosterone." If you don't know what "testis" means, then for goodness sakes look it up. FEMALES DON'T HAVE THEM!!!
  • Apr 2, 2022, 02:10 PM
    Wondergirl
    That article begins after gender has been established and external sex organs have formed.
  • Apr 2, 2022, 02:11 PM
    jlisenbe
    Your own article clearly states that the Y chromosome is responsible for the development of testis and thus testosterone.
  • Apr 2, 2022, 02:12 PM
    Wondergirl
    Quote:

    Originally Posted by jlisenbe View Post
    Your own article clearly states that the Y chromosome is responsible for the development of testis and thus testosterone.

    Yes! When? After what has happened?
  • Apr 2, 2022, 02:16 PM
    jlisenbe
    It's hopeless. You didn't even read the article or you would never have made such a comment. Gender is established at the moment of conception. It's a well known truth that everyone but you, evidently, is well aware of. Even your own article, at this point the worst enemy of your now hopelessly forgotten "testosterone bath" and assertion that TG individuals begin with a different hormonal makeup than others have, says this. "Being XX or XY makes you female or male, of course..." Do you really not understand that???

    Quote:

    After what has happened?
    Concerning your fake idea, the primary point is more like, "BEFORE what happens?" It is BEFORE testosterone is produced, so females are not subject to a "testosterone bath". Good grief. Could it be any more plain???
  • Apr 2, 2022, 02:25 PM
    Wondergirl
    Quote:

    Originally Posted by jlisenbe View Post
    It's hopeless. You didn't even read the article or you would never have made such a comment. Gender is established at the moment of conception.

    Nope. Not true. I'm done with this. And since you must have had a double testosterone bath in the womb, you will force yourself to post the last word in this discussion.
  • Apr 2, 2022, 02:32 PM
    jlisenbe
    Indeed I will. Your own article, as I noted above, said that. If you didn't like it, then you shouldn't have posted it.

    Quote:

    "Being XX or XY makes you female or male, of course..." Do you really not understand that???
  • Apr 2, 2022, 02:37 PM
    Wondergirl
    "Being XX or XY makes you female or male, of course..." Do you really not understand that???
    Quote:

    Originally Posted by jlisenbe View Post
    Your own article, as I noted above, said that. If you didn't like it, then you shouldn't have posted it.

    That comes later. Not at conception.
  • Apr 2, 2022, 02:45 PM
    jlisenbe
    Nope. It happens at the moment of conception. "It is thus the male's sperm that determines the sex of each offspring in such species." This is because the female can only contribute an X chromosome, but the male can contribute either an X or Y. If it's a Y, then the offspring is male from the very beginning. The fertilized egg's gender has already been established at that point.

    https://en.wikipedia.org/wiki/Sex_chromosome

    Dear WG, I am stating nothing that has not been well known for decades. Sex chromosomes were discovered early in the 20th century.

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