Hi Erinn,
Yes, hives can be a sign of an allergic reaction to Vicodin. Though, as you've had the rash for four months, and this is generally considered a fairly serious reaction, it would be difficult to say for sure if this is the cause. Either way though, I would not take the prescription any further, and it would be good to contact a doctor as soon as possible to look into it. If this is the cause, it should subside in time, though I would still seek medical attention fairly promptly, just to be safe.
Take care.
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