[silynthia]

I'm 43 and just missed my period. I had all the pms symptoms but never started. I still am having breast tenderness. Could it be perimenopause?

[jenniepepsi]

Mmm have you been having sex? Even at 43 you could be pregnant unless there has been no sex.

Its possible to start menopause in your 40s however, so I would say speak to your doctor, as both possibilitys should be dealt with right away.