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Gernald
May 1, 2008, 02:16 PM
What is the purpose of the sodium postssium pump?
I know how it works but my book fails to say what the point of it is.

Thanks!

templelane
May 1, 2008, 02:25 PM
It's creates a concentration gradient across the cell membrane so that it can be used to create a membrane potential in the cell (esecially in neurons.)

It also creates a membrane potential as 3 sodiums are pumped for every two potassiums.

The concentration gradient and the potential energy from this can be used a bit like charging a battery. Positive charge builds up outside of the cell.

Look up neurons and that should explain the main reasons for it.

Gernald
May 1, 2008, 02:31 PM
Thanks so much...
Just another quick question... what's an example of a voltage gradient? Is an action potential (same as membrane potential?) a voltage gradient?

Thanks again for any help!

templelane
May 1, 2008, 02:44 PM
A voltage gradient is a difference in electral potential over the cell membrane.

An action potential is something a little bit different, have a read of this site, I think you will find it helpful

Nerve Impulses (http://www.biologymad.com/NervousSystem/nerveimpulses.htm)

The action potential is the change in the voltage gradient, so cannot be used as an example.

If I were asked to give an example of a voltage gradient I would quote the K, Ca and Na concentrations and say outside of the cell is more positive. I would then say the mV that you can record inside of the resting cell (~-70mV) and outside* (using a voltage clamp to measure it- talking about experimental procedures always gives you extra marks).

*I've seen a few of these use whatever your lecture notes say.

templelane
May 1, 2008, 02:48 PM
Definitions

Voltage Gradient
Sect. 1, Ch. 1: Definition of Voltage Gradient (http://www.lib.mcg.edu/edu/eshuphysio/program/section1/1ch1/s1ch1_12.htm)

Membrane Potential- what results form the voltage gradient
Membrane potentials (http://www.cvphysiology.com/Arrhythmias/A007.htm)

Gernald
May 1, 2008, 02:55 PM
Okay thanks!

You've just saved part of my biology grade! :-)