I have an older Lenovo G480, 4G ram, Win 10.

The USB2 and USB3 ports are inoperable.

I have disable both ports, rebooted then enabled them. No difference.

I have also uninstalled both ports, rebooted and no difference.

All Root hubs are set to no allow the PC to shut the port off.

I'm at a loss, what's the next move?

Can you see the ports in your BIOs and are the drivers installed properly? Are the ports asleep? Or actually powered off in a permanent fashion?

I did not look in the BIOS, how can I get to it?

On some machines you can use F8 or F10 at startup. Others require you to press ESC. It should lead you to your bios and you can see if the machine sees the hub or not.

Here is a link to the PDF user manual.

http://r.search.yahoo.com/_ylt=AwrBTz21Z5dYf_UAZ5xXNyoA;_ylu=X3oDMTByZnU4cmN pBGNvbG8DYmYxBHBvcwM5BHZ0aWQDBHNlYwNzcg--/RV=2/RE=1486346294/RO=10/RU=http%3a%2f%2fwww.lenovo.com%2fshop%2famericas%2 fcontent%2fuser_guides%2fgseries_ug_en.pdf/RK=0/RS=uXaHwWCBFTS3H58WfhwCo986VYQ-