[shot1k]

I was surprised at how many posts I had seen about ETG testing. Much of it has been useful but I have not seen anything on how much or little metabolism can play a role. The closest I have pushed is 4 beers about 40 hours before an ETG and passed. I do not do this often because I do make an honest effort to remain abstinant but I have slipped up a few times. This time I took the cake. About 9 drinks 64-68 hours before the test. When I was younger and smoked pot I could smoke regularly, go for two- five or six mile runs 3 days apart and be clean within a day or 2 afterwards. I know that THC is stored in fat cells so I could count on this to work. But does excersise and metabolism play a major role in ETG levels? Also, related but not the same I heard that larger muscle masses produce an enzyme which eliminates some alcohol ingested without it being processed through the liver. Is that true? I know from multiple experiences that 10 or 11 drinks over about 4 hours will put me at a BAC of about .14 forty five minutes after the last drink. I do not know if that is a good or bad thing as far as ETG testing. Does any one with actual knowledge have any answers?

[shot1k]

I would like to add that I get in almost as much trouble for a deluted tests as I would for failing. I take creatine hydrochloride for excersise which I believes gives me a little leg room on the urine concentration but I stay well hydrated so it is easy to even accidentally dilute a test. So I have generally been dehydrating myself before tests. Would that still be a bad decision 64 hours after consumption?

[DrBill100]

[QUOTE=shot1k;2959746 .... but I have not seen anything on how much or little metabolism can play a role........related but not the same I heard that larger muscle masses produce an enzyme which eliminates some alcohol ingested without it being processed through the liver. ....[/QUOTE]

There are no studies to date dealing with metabolism in relation to EtG elimination. There are elimination studies but none correlated to metabolic rate.

On the downside of this, there is no known relationship between amount of ethanol consumed and the amount of EtG produced. It is widely variable in each of the studies performed.

The primary enzyme responsible for ethanol metabolism is Alcohol Dehydrogenase (ADH). Mostly in the liver (about 80%) but ADH is present throughout the alimentary canal. Some alcohol is metabolized in the stomach (18-20%) and it is assumed this does not create EtG. That could very easily be wrong.

EtG research has been very limited. The vast majority of research has been directed to detecting EtG with little concern for describing the mechanism(s) of production and elimination.

During the process of absorption ethanol stores in muscle tissue due to water content. There is no indication of an enzyme system therein that would expedite metabolism.

[shot1k]

Im also curious about the elimination curve. Is it known to be a constant amount or percent that is eliminated vs time. The time difference between a positive being declaired at 500ng doesn't sound much different than one being declaired at 100ng if the amount of ETG produced is directly related to alcohol consumed. Even if the amount produced is subjective per individual it should be directly related whether it be in small or large ammounts? Would it also be eliminated in a constant manor? I have a lot of friends in the chemical and alcohol recovery community so this has been a discussion that pops up and I am sure will again. And I seem to be the first guy asked in questionable times. Unfortunately my only real knowledge is from where I have screwed up.