Every night when I lie down, doesn't matter what position, my right leg from my thigh all the way to toes and my right arm from my shoulder all the way to my fingers goes numb and tingly. What could be causing this?

How old is your mattress?

Do you lie flat on your back?

My mattress is only 2 years old. It is a tempur-pedic mattress as well. I lie in all different positions. Never one specific position and it happens no matter the position.

You don't have any problems while standing or sitting or bending over?

When did the problem begin?

No trouble with standing or bending. Problem began about a week ago but is getting worse

It could be a couple of nerves are getting pinched for some reason. Time to visit your doctor or maybe a good chiropractor? You need to have someone with knowledge of the human body to poke and prod you.

If you lie down on the sofa or the floor, does the numbness happen?