Whenever I go online my computer constantly, every few minutes, interrupts whatever I am doing with audio commercials.. It doesn't seem to matter what browser I use: Chrome, Firefox, Seamonkey, Explorer... These commercials break in during videos I'm watching, whatever... HELP!

Run CCleaner.

I have. Unfortunately it has no effect

Do you have any other open tabs and when did you last scan for adware ?

Malware Bytes.

Can you post the screen shot of that audio commercials?