How to teach english to my wife, she don't know english because she is from urdu medium and know to read english but don't know d meaning of what she is reading, she have a basic knowledge of talking and understanding english

The best would be to sign her up for a class.
For other ideas see for example here:
How to Learn English From Urdu | The Classroom | Synonym on Synonym (http://classroom.synonym.com/learn-english-urdu-2376.html)

For learning vocabulary you could use www.kahrds.com
You create your own study sets with the words you want her to learn and the computer generates games so you can play and test yoruself on what you've learned.