If you took one Lortab on Friday at 6 pm will you test positive on a drug screening on Thursday morning?

If you have a prescription for it from a doctor for it... you would be OK.

If you took one Lortab on Friday at 6 pm will you test positive on a drug screening on Thursday morning?

One dose would probably be eliminated in that time span and would not be tested for in a standard drug screen. Can be detected in an expanded panel test.

The problem with hydrocodone (including Lortab) is that it tends to cross-react with opiate panels on many of the standard immunoassays creating a false positive.

R. Baselt, Disposition of Toxic Drugs and Chemicals in Man (http://en.wikipedia.org/wiki/Hydrocodone#Pharmacokinetics), 9th edition, Biomedical Publications, Seal Beach, CA, 2011, pp. 812-814

One dose probably would probably be eliminated in that time span and would not be tested for in a standard drug screen. Can be detected in an expanded panel test.

The problem with hydrocodone (including Lortab) is that it tends to cross-react with opiate panels on many of the standard immunoassays creating a false positive.

R. Baselt, Disposition of Toxic Drugs and Chemicals in Man (http://en.wikipedia.org/wiki/Hydrocodone#Pharmacokinetics), 9th edition, Biomedical Publications, Seal Beach, CA, 2011, pp. 812-814

Thanks Dr. Bill, your answers are much appreciated.