I want to know if there's a Hebrew word that means 'total destruction', but I can't read Hebrew symbols so I'd like the word as it's pronounced in English.

Are we talking about ancient Hebrew or modern Hebrew? In ancient (biblical) Hebrew it's hard to represent in English because it starts with one of those "clear your throat" sounds. I don't know if it's the same in modern Hebrew, but for what it's worth, the biblical word is

Khe-rem with accent on the first syllable. Both vowels are short "e".