How do I talk to my best friend about y we r not ask close as we use to and how its affecting me and why has are friendship changed?

Just ask her. As you sound genuinely concerned it may be better to ask her face to face but if you do not feel up to that then maybe send her an email explaining the changes you have noticed in your friendship. Try to speak to her in a calm manner and not in an accusatory one, remember it may be that she has a few things on her mind too or she could feel that you are the one who has changed. Be ready to talk things through, but just make sure you explain to her how you feel. Good luck, hope it all goes well.

Definitely talk to your friend, and when you do I strongly suggest you do it face-to-face. On top of that I also advise that in these sorts of situations you use "I" Language.

In other words, don't say things like "You've been acting differently" or "You haven't been talking to me as much." Instead say things like "I feel like things are different between us" and "I feel like we haven't been talking as much as we used to."

By using the pronoun "I" your friend won't feel like you are accusing him/her. Good Luck!

The only realistic thing to do is to come straight out and ask and say everything you've said here.

I agree with the others here and a face to face no blame conversation to clear the air is needed.

how do i talk to my bestfriend about y we r not ask close as we use to and how its affecting me and why has are friendship changed?
These things happen! Me and my friends all split up over her boyfriend messing our friendship up! We'v got it sorted now thou! Call the shots and tell her how u feel! It'll be OK!