My 7.3 powerstroke will start and run for a few minutes and die. It will start after setting for few hours, any ideal

Could be a weak fuel pump. Read Item 6 in the link below:

https://www.askmehelpdesk.com/cars-trucks/faq-how-troubleshoot-repair-maintain-hondas-selected-other-vehicles-46563-8.html#post1415281

Following the steps above should help you isolate the problem. Be sure to change both fuel filters, if they have not been done recently.